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TGFβ1 Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0036

库存:现货
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Catalog No :IPB0036
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000 IF: 1:50-1:200
Gene Name:TGFB1 TGFB
Protein Name:Transforming growth factor beta-1, TGF-β1, TGF b
Human Gene Id:7040
Swiss-Prot:P01137
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix [Transforming growth factor beta-1]: Secreted
MW:44341
Background:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer The mature peptide may also form heterodimers with other TGFB family members This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha

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