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Caspase-3 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0034

库存:现货
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Catalog No :IPB0034
Reactivity:Human; Monkey
Applications:WB; ELISA
Dilution:WB: 1:500-1:2000 ELISA: 1:40000
Gene Name:CASP3
Protein Name:Caspase3
Human Gene Id:836
Swiss-Prot:P42574
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm
MW:31608
Background:This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10 It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease Alternative splicing of this gene results in two transcript variants that encode the same protein

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