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| Catalog No ： | IPB0033 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; ELISA |
| Dilution： | WB: 1:500-1:2000 ELISA: 1:10000 |
| Gene Name： | CCND1 |
| Protein Name： | G1/S-specific cyclin-D1 |
| Human Gene Id： | 595 |
| Swiss-Prot： | P24385 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus Cytoplasm Nucleus membrane Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated to the nucleus through interaction with KIP:CIP family members |
| MW： | 33729 |
| Background： | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle Cyclins function as regulators of CDK kinases Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1:S transition This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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