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| Catalog No ： | IPB0032 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | IF/ICC; WB; IHC-p; ELISA |
| Dilution： | IF: 1:50-200 WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | MAPK1:MAPK3 |
| Protein Name： | Mitogen-activated protein kinase 3 |
| Human Gene Id： | 5595 |
| Swiss-Prot： | P27361:P28482 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus Membrane, caveola Cell junction, focal adhesion Autophosphorylation at Thr-207 promotes nuclear localization (PubMed:19060905) PEA15-binding redirects the biological outcome of MAPK3 kinase-signaling by sequestering MAPK3 into the cytoplasm (By similarity) |
| MW： | 43136 |
| Background： | The protein encoded by this gene is a member of the MAP kinase family MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets Alternatively spliced transcript variants encoding different protein isoforms have been described |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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