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| Catalog No ： | IPB0031 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | MTOR |
| Protein Name： | Serine/threonine-protein kinase mTOR |
| Human Gene Id： | 2475 |
| Swiss-Prot： | P42345 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side Lysosome Cytoplasm Nucleus, PML body Microsome membrane Lysosome membrane Cytoplasmic vesicle, phagosome Shuttles between cytoplasm and nucleus Accumulates in the nucleus in response to hypoxia (By similarity) Targeting to lysosomes depends on amino acid availability and RRAGA and RRAGB (PubMed:18497260, PubMed:20381137) Lysosome targeting also depends on interaction with MEAK7 Translocates to the lysosome membrane in the presence of TM4SF5 (PubMed:30956113) |
| MW： | 288892 |
| Background： | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex The ANGPTL7 gene is located in an intron of this gene |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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