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TNF-α Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0028

库存:现货
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Catalog No :IPB0028
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000   IHC-p: 1:100-1:200   ELISA: 1:20000   IF: 1:50-1:200
Gene Name:TNF TNFA TNFSF2
Protein Name:Tumor necrosis factor
Human Gene Id:7124
Swiss-Prot:P01375
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type II membrane protein [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein [Tumor necrosis factor, soluble form]: Secreted [C-domain 1]: Secreted [C-domain 2]: Secreted
MW:16KD
Background:This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily This cytokine is mainly secreted by macrophages It can bind to, and thus functions through its receptors TNFRSF1A:TNFR1 and TNFRSF1B:TNFBR This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer Knockout studies in mice also suggested the neuroprotective function of this cytokine

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