中文
English
| Catalog No ： | IPB0025 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | IF/ICC; WB; IHC-p; IP; ELISA |
| Dilution： | IF: 1:50-200 WB: 1:500-1:2000 IP: 1:50 IHC: 1:50-1:200 ELISA: 1:40000 |
| Gene Name： | HIF1A |
| Protein Name： | Hypoxia-inducible factor 1-alpha |
| Human Gene Id： | 3091 |
| Swiss-Prot： | Q16665 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus Nucleus speckle Colocalizes with HIF3A in the nucleus and speckles (By similarity) Cytoplasmic in normoxia, nuclear translocation in response to hypoxia (PubMed:9822602) |
| MW： | 92670 |
| Background： | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease Alternatively spliced transcript variants encoding different isoforms have been identified for this gene |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
join our baijia list to stay up to date and get notices about our new releases!
