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| Catalog No. ： | IMB0205 |
| Reactivity： | Human;Mouse;Monkey |
| Applications： | WB; FCM; ELISA |
| Gene Name： | STK11 |
| Protein Name： | Serine/threonine-protein kinase 11 |
| Human Gene Id： | 6794 |
| Swiss-Prot： | Q15831 |
| Formulation： | Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. |
| Source： | Monoclonal, Mouse |
| Dilution： | WB: 1:500-1:2000 FCM: 1:200-1:400 ELISA: 1:10000 |
| PurIF:ication： | Affinity purIF:ication |
| Concentration： | nan |
| Storage&Stability： | -20°C/1 year |
| Background： | This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008], |
| Subcellular Location.： | Nucleus. Cytoplasm. Membrane. Mitochondrion. A small fraction localizes at membranes (By similarity). Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta). Translocates to the mitochondrion during apoptosis. PTEN promotes cytoplasmic localization. [Isoform 2]: Nucleus. Cytoplasm. Predominantly nuclear, but translocates to the cytoplasm in response to metformin or peroxynitrite treatment. |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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