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4E-BP1 Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0176

库存:现货
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Catalog No. :IMB0176
Reactivity:Human
Applications:WB; ELISA
Gene Name:EIF:4EBP1
Protein Name:Eukaryotic translation initiation factor 4E-binding protein 1
Human Gene Id:1978
Swiss-Prot:Q13541
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF:4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF:4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF:4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
Subcellular Location.:nucleoplasm, cytoplasm, cytosol, protein complex.
BiowMW:nan

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