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Pan Methylated Lysine Monoclonal Antibody(Mix)

验证数据库

¥2080.00元/format:100ul

目录号:IMB0159

库存:现货
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产品信息

Catalog No. :IMB0159
Reactivity:Species independent
Applications:WB; IHC-p
Gene Name:nan
Protein Name:nan
Human Gene Id:nan
Swiss-Prot:nan
Formulation:PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:1000-2000 IHC: 1:200-500
PurIF:ication:The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using epitope-specIF:ic immunogen.
Concentration:nan
Storage&Stability:-20°C/1 year
Background:Methylation of lysine residues is a common regulatory posttranslational modIF:ication (PTM) that results in the mono-, di-, or tri-methylation of lysine at ε-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism: class I methyltransferases or seven β strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA. Six methyl-lysine-interacting protein families are distinguished based on binding domains: mBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display dIF:ferential binding preferences based on lysine methylation state. KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modIF:y tri-methyl lysine residues.
Subcellular Location.:nan
BiowMW:nan

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