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| Catalog No. ： | IMB0155 |
| Reactivity： | Human;Mouse;Rat |
| Applications： | IF/ICC; IHC-p |
| Gene Name： | COL1A1 |
| Protein Name： | Collagen alpha-1(I) chain (Alpha-1 type I collagen) |
| Human Gene Id： | 1277/1278 |
| Swiss-Prot： | P02452 |
| Formulation： | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source： | Monoclonal, Mouse |
| Dilution： | IF: 1:50-200 IHC-p: 1:50-300 |
| PurIF:ication： | The antibody was affinity-purIF:ied from mouse antiserum by affinity-chromatography using epitope-specIF:ic immunogen. |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Background： | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identIF:ied for this gene. [provided by R. Dalgleish, Feb 2008], |
| Subcellular Location.： | Secreted, extracellular space, extracellular matrix. |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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