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TBP/TATA Binding Protein Monoclonal Antibody(1F6)

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¥2080.00元/format:100ul

目录号:IMB0143

库存:现货
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Catalog No. :IMB0143
Reactivity:Human;Rat;Mouse
Applications:IHC-p;
Gene Name:TBP
Protein Name:TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Human Gene Id:6908
Swiss-Prot:P20226
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Monoclonal, Mouse
Dilution:IHC: 1:50-200
PurIF:ication:The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen.
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Background:Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modIF:y general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin
Subcellular Location.:Nucleus.
BiowMW:nan

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