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EnglishCatalog No. : | IMB0135 |
Reactivity: | Human;Mouse;Rat;Bovine;Dog;Goat;Pig;Rabbit;sheep |
Applications: | WB; IF/ICC |
Gene Name: | PPARG |
Protein Name: | Peroxisome prolIF:erator-activated receptor gamma |
Human Gene Id: | 5468 |
Swiss-Prot: | P37231 |
Formulation: | PurIF:ied mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:1000-1:2000 IF: 1:100-1:500 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes a member of the peroxisome prolIF:erator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte dIF:ferentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode dIF:ferent isoforms have been described. [provided by RefSeq, Jul 2008], |
Subcellular Location.: | Nucleus. Cytoplasm. Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation. |
BiowMW: | nan |
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