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p63 Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0134

库存:现货
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Catalog No. :IMB0134
Reactivity:Human;Mouse;Rat;Monkey
Applications:WB; IHC-p; ELISA
Gene Name:TP63
Protein Name:Tumor protein 63
Human Gene Id:8626
Swiss-Prot:Q9H3D4
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 IHC: 1:200-1:1000 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding dIF:ferent isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim
Subcellular Location.:Nucleus.
BiowMW:nan

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