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PERK Monoclonal Antibody

验证数据库

¥2080.00元/format:100ul

目录号:IMB0132

库存:现货
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Catalog No. :IMB0132
Reactivity:Human
Applications:WB; ELISA
Gene Name:EIF:2AK3
Protein Name:Eukaryotic translation initiation factor 2-alpha kinase 3
Human Gene Id:9451
Swiss-Prot:Q9NZJ5
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Subcellular Location.:Endoplasmic reticulum membrane; Single-pass type I membrane protein.
BiowMW:nan

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