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Oct-3/4 Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0131

库存:现货
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Catalog No. :IMB0131
Reactivity:Human
Applications:WB; FCM; IF/ICC
Gene Name:POU5F1
Protein Name:POU domain class 5 transcription factor 1
Human Gene Id:5460
Swiss-Prot:Q01860
Formulation:PurIF:ied mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:1000-1:2000 FCM: 1:100-1:200 IF: 1:100-1:500
PurIF:ication:Affinity purIF:ication
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Background:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identIF:ied on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],
Subcellular Location.:Cytoplasm. Nucleus. Expressed in a dIF:fuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus.
BiowMW:nan

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