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NFκB-p65 Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0130

库存:现货
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Catalog No. :IMB0130
Reactivity:Human;Mouse
Applications:WB; ELISA
Gene Name:RELA
Protein Name:Transcription factor p65
Human Gene Id:5970
Swiss-Prot:Q04206
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specIF:ic inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specIF:ic genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding dIF:ferent isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Subcellular Location.:Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalized with DDX1 in the nucleus upon TNF-alpha induction. Colocalizes with GFI1 in the nucleus after LPS stimulation. Translocation to the nucleus is impaired in L.monocytogenes infection.
BiowMW:nan

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