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EnglishCatalog No. : | IMB0128 |
Reactivity: | Human |
Applications: | IHC-p; ELISA |
Gene Name: | MKI67 |
Protein Name: | Antigen KI-67 |
Human Gene Id: | 4288 |
Swiss-Prot: | P46013 |
Formulation: | Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | IHC: 1:200-1:1000 ELISA: 1:10000 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes a nuclear protein that is associated with and may be necessary for cellular prolIF:eration. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009], |
Subcellular Location.: | Chromosome. Nucleus. Nucleus, nucleolus. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface. Associates with satellite DNA in G1 phase. Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. |
MW: | 360kd |
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