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EnglishCatalog No. : | IMB0127 |
Reactivity: | Human |
Applications: | WB; IHC-p; ELISA |
Gene Name: | ERN1 |
Protein Name: | Serine/threonine-protein kinase/endoribonuclease IRE1 |
Human Gene Id: | 2081 |
Swiss-Prot: | O75460 |
Formulation: | Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:500-1:2000 IHC: 1:200-1:1000 ELISA: 1:10000 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008], |
Subcellular Location.: | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
BiowMW: | nan |
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