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ERK 1 Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0114

库存:现货
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Catalog No. :IMB0114
Reactivity:Human;Mouse;Rat;Monkey
Applications:WB; IHC-p; IF/ICC; FCM; ELISA
Gene Name:MAPK3
Protein Name:Mitogen-activated protein kinase 3
Human Gene Id:5595
Swiss-Prot:P27361
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 IHC: 1:200-1:1000 IF: 1:200-1:1000 FCM: 1:200-1:400 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as prolIF:eration, dIF:ferentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding dIF:ferent protein isoforms have been described. [provided by RefSeq, Jul 2008],
Subcellular Location.:Cytoplasm. Nucleus. Membrane, caveola. Cell junction, focal adhesion. Autophosphorylation at Thr-207 promotes nuclear localization. PEA15-binding redirects the biological outcome of MAPK3 kinase-signaling by sequestering MAPK3 into the cytoplasm (By similarity).
BiowMW:nan

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