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| Catalog No. ： | IMB0094 |
| Reactivity： | Human |
| Applications： | WB |
| Gene Name： | CYP7A1 |
| Protein Name： | Cholesterol 7-alpha-monooxygenase |
| Human Gene Id： | 1581 |
| Swiss-Prot： | P22680 |
| Formulation： | PurIF:ied mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
| Source： | Monoclonal, Mouse |
| Dilution： | WB: 1:1000-1:2000 |
| PurIF:ication： | Affinity purIF:ication |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Background： | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010], |
| Subcellular Location.： | Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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