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EnglishCatalog No. : | IMB0088 |
Reactivity: | Human |
Applications: | WB; ELISA |
Gene Name: | CD86 |
Protein Name: | T-lymphocyte activation antigen CD86 |
Human Gene Id: | 942 |
Swiss-Prot: | P42081 |
Formulation: | Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:500-1:2000 ELISA: 1:10000 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding dIF:ferent isoforms.[provided by RefSeq, May 2011], |
Subcellular Location.: | Cell membrane; Single-pass type I membrane protein. |
BiowMW: | nan |
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