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EnglishCatalog No. : | IMB0086 |
Reactivity: | Human |
Applications: | WB |
Gene Name: | pecam1 |
Protein Name: | nan |
Human Gene Id: | 5175 |
Swiss-Prot: | P16284 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:1000 |
PurIF:ication: | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using epitope-specIF:ic immunogen. |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Background: | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010], |
Subcellular Location.: | Cell membrane; Single-pass type I membrane protein. Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. [Isoform Long]: Cell membrane; Single-pass type I membrane protein. Membrane raft. Cell junction. Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. |
BiowMW: | nan |
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