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| Catalog No. ： | IMB0073 |
| Reactivity： | Human |
| Applications： | IF/ICC; WB; IHC-p; |
| Gene Name： | PARP1 |
| Protein Name： | Poly [ADP-ribose] polymerase 1 |
| Human Gene Id： | 142 |
| Swiss-Prot： | P09874 |
| Formulation： | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Source： | Monoclonal, Mouse |
| Dilution： | IF: 1:50-200 WB: 1:2000-5000 IHC: 1:50-300 |
| PurIF:ication： | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
| Concentration： | nan |
| Storage&Stability： | -20°C/1 year |
| Background： | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modIF:ies various nuclear proteins by poly(ADP-ribosyl)ation. The modIF:ication is dependent on DNA and is involved in the regulation of various important cellular processes such as dIF:ferentiation, prolIF:eration, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008], |
| Subcellular Location.： | Nucleus. Nucleus, nucleolus. Chromosome. Localizes to sites of DNA damage. |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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