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EnglishCatalog No. : | IMB0067 |
Reactivity: | Human;Rat;Mouse |
Applications: | WB; IF/ICC; IHC-p |
Gene Name: | MAP1LC3A |
Protein Name: | LC3A |
Human Gene Id: | 84557 |
Swiss-Prot: | Q9H492 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:1000-2000 IHC: 1:100-200 IF: 1:200 |
PurIF:ication: | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Background: | MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding dIF:ferent isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012], |
Subcellular Location.: | Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Endomembrane system; Lipid-anchor. Cytoplasm, cytoskeleton. LC3-II binds to the autophagic membranes. |
BiowMW: | nan |
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