中文
EnglishCatalog No. : | IMB0048 |
Reactivity: | Human;Mouse;Rat |
Applications: | WB |
Gene Name: | VIM |
Protein Name: | Vimentin |
Human Gene Id: | 7431 |
Swiss-Prot: | P08670 |
Formulation: | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:1000-3000 |
PurIF:ication: | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterIF:ication. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. |
Subcellular Location.: | Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane. |
BiowMW: | 53652 |
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