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EnglishCatalog No. : | IMB0031 |
Reactivity: | Human;Rat;Mouse |
Applications: | WB; IHC-p; IF/ICC |
Gene Name: | GFAP |
Protein Name: | Glial fibrillary acidic protein |
Human Gene Id: | 2670 |
Swiss-Prot: | P14136 |
Formulation: | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:2000-5000 IF: 1:200 IHC: 1:50-300 |
PurIF:ication: | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Subcellular Location.: | Cytoplasm. Associated with intermediate filaments. |
BiowMW: | 49880 |
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