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| Catalog No. ： | IMB0024 |
| Reactivity： | Human;Rat;Mouse |
| Applications： | WB; IHC-p; |
| Gene Name： | MAPK1/MAPK3 |
| Protein Name： | MAPK1/MAPK3 |
| Human Gene Id： | 5594/5595 |
| Swiss-Prot： | P27361/P28482 |
| Formulation： | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source： | Monoclonal, Mouse |
| Dilution： | WB: 1:1000-2000 IHC: 1:100-200 |
| PurIF:ication： | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Background： | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as prolIF:eration, dIF:ferentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding dIF:ferent protein isoforms have been described. [provided by RefSeq, Jul 2008], |
| Subcellular Location.： | Cytoplasm. Nucleus. Membrane, caveola. Cell junction, focal adhesion. Autophosphorylation at Thr-207 promotes nuclear localization (PubMed:19060905). PEA15-binding redirects the biological outcome of MAPK3 kinase-signaling by sequestering MAPK3 into the cytoplasm (By similarity). |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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