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Ki 67 Monoclonal Antibody(4A8)

¥2080.00元/format:100ul

目录号:IMB0021

库存:现货
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Catalog No. :IMB0021
Reactivity:Human;Mouse;Rat
Applications:IHC-P; IF/ICC;
Gene Name:MKI67
Protein Name:Antigen KI-67
Human Gene Id:4288
Swiss-Prot:P46013
Formulation:PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source:Monoclonal, Mouse
Dilution:IHC: 1:200 IF: 1:50-200
PurIF:ication:The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen.
Concentration:nan
Storage&Stability:-20°C/1 year
Background:This gene encodes a nuclear protein that is associated with and may be necessary for cellular prolIF:eration. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.
Subcellular Location.:Chromosome. Nucleus. Nucleus, nucleolus. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226). Associates with satellite DNA in G1 phase (PubMed:9510506). Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubMed:15896774, PubMed:22002106). Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix.
BiowMW:358694

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