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CD3E Monoclonal Antibody

验证数据库

¥2080.00元/format:100ul

目录号:IMB0020

库存:现货
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Catalog No. :IMB0020
Reactivity:Human
Applications:WB; FCM; ELISA
Gene Name:CD3E
Protein Name:T-cell surface glycoprotein CD3 epsilon chain
Human Gene Id:916
Swiss-Prot:P07766
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 FCM: 1:200-1:400 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Subcellular Location.:Cell membrane; Single-pass type I membrane protein.
BiowMW:nan

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