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| Catalog No. ： | IMB0019 |
| Reactivity： | Human;Mouse;Rat;Chicken |
| Applications： | IF/ICC; WB; IHC-p |
| Gene Name： | CASP3 |
| Protein Name： | Caspase3 |
| Human Gene Id： | 836 |
| Swiss-Prot： | P42574 |
| Formulation： | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Source： | Monoclonal, Mouse |
| Dilution： | IF: 1:50-200 WB: 1:500-1000 IHC: 1:100-200 |
| PurIF:ication： | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using epitope-specIF:ic immunogen. |
| Concentration： | nan |
| Storage&Stability： | -20°C/1 year |
| Background： | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
| Subcellular Location.： | Cytoplasm. |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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