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EnglishCatalog No. : | IMB0008 |
Reactivity: | Human |
Applications: | WB; ELISA |
Gene Name: | IL2 |
Protein Name: | Interleukin-2 |
Human Gene Id: | 3558 |
Swiss-Prot: | P60568 |
Formulation: | Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:500-1:2000 ELISA: 1:10000 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | The protein encoded by this gene is a secreted cytokine that is important for the prolIF:eration of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
Subcellular Location.: | Secreted. |
BiowMW: | nan |
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