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EnglishCatalog No. : | IMB0006 |
Reactivity: | Human |
Applications: | FCM; ELISA |
Gene Name: | CD247 |
Protein Name: | T-cell surface glycoprotein CD3 zeta chain |
Human Gene Id: | 919 |
Swiss-Prot: | P20963 |
Formulation: | Lyophilized from a 0.2μm filtered solution in PBS. |
Source: | Monoclonal, Mouse |
Dilution: | FCM: 1:200-1:400 ELISA: 1:10000 |
PurIF:ication: | Affinity purIF:ication |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Background: | The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Subcellular Location.: | Cell membrane; Single-pass type I membrane protein. |
BiowMW: | nan |
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