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EnglishCatalog No. : | IML0855 |
Reactivity: | Human |
Applications: | IHC-p; IF(paraffin section) |
Gene Name: | MUC4 |
Protein Name: | MUC4 |
Human Gene Id: | 4585 |
Swiss-Prot: | Q99102 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.173% sodium azide. |
Source: | Monoclonal, Mouse:IgG2a, Kappa |
Dilution: | IHC-p: 1:100-200 IF: 1:100-500 |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 0.4mg:mL |
Storage&Stability: | -20°C:1 year |
Background: | The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008], |
Subcellular Location: | proteinaceous extracellular matrix,extracellular space,Golgi lumen,integral component of plasma membrane,membrane,integral component of membrane,vesicle,extracellular exosome, |
BiowMW: | nan |
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