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EnglishCatalog No. : | IML0854 |
Reactivity: | Human |
Applications: | IHC-p; IF(paraffin section) |
Gene Name: | CD163 M130 |
Protein Name: | CD163 |
Human Gene Id: | 9332 |
Swiss-Prot: | Q86VB7 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.172% sodium azide. |
Source: | Monoclonal, Mouse:IgG1, Kappa |
Dilution: | IHC-p: 1:100-200 IF: 1:100-500 |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 0.905mg:mL |
Storage&Stability: | -20°C:1 year |
Background: | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin:haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011], |
Subcellular Location: | Tonsil, Placenta, Colon |
BiowMW: | nan |
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