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MUM1 mouse mAb(ABT080)

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¥1900.00元/format:100ul

目录号:IML0850

库存:现货
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Catalog No. :IML0850
Reactivity:Human
Applications:IHC-p; IF(paraffin section)
Gene Name:IRF4 MUM1
Protein Name:MUM1
Human Gene Id:3662
Swiss-Prot:Q15306
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.168% sodium azide.
Source:Monoclonal, Mouse:IgG1, Kappa
Dilution:IHC-p: 1:100-200 IF: 1:100-500
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:0.45mg:mL
Storage&Stability:-20°C:1 year
Background:The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010],
Subcellular Location:Colon, Tonsil
BiowMW:nan

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