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| Catalog No. ： | IML0819 |
| Reactivity： | Human |
| Applications： | IHC-p; IF(paraffin section) |
| Gene Name： | CTNNB1 CTNNB OK:SW-cl.35 PRO2286 |
| Protein Name： | Beta-catenin |
| Human Gene Id： | 1499 |
| Swiss-Prot： | P35222 |
| Formulation： | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.131% sodium azide. |
| Source： | Monoclonal, Mouse:IgG2b, Kappa |
| Dilution： | IHC-p: 1:100-200 IF: 1:100-500 |
| Purification： | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Concentration： | 1.27mg:mL |
| Storage&Stability： | -20°C:1 year |
| Background： | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016], |
| Subcellular Location： | spindle pole,nucleus,nucleoplasm,transcription factor complex,nuclear euchromatin,cytoplasm,centrosome,cytosol,plasma membrane,cell-cell junction,adherens junction,cell-cell adherens junction,fascia adherens,bicell |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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