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EnglishCatalog No. : | IML0191 |
Reactivity: | Human; Mouse |
Applications: | IHC-p |
Gene Name: | CD63 MLA1 TSPAN30 |
Protein Name: | CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63) |
Human Gene Id: | 967 |
Swiss-Prot: | P08962 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Monoclonal, Mouse:IgG2a, Kappa |
Dilution: | IHC-p: 1:100-200 |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 1.9mg:mL |
Storage&Stability: | -20°C:1 year |
Background: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
Subcellular Location: | Cytoplasmic, Membranous |
BiowMW: | nan |
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