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| Catalog No. ： | IML0155 |
| Reactivity： | Human; Mouse |
| Applications： | IHC-p |
| Gene Name： | CR1 C3BR |
| Protein Name： | Complement receptor type 1 (C3b:C4b receptor) (CD antigen CD35) |
| Human Gene Id： | 1378 |
| Swiss-Prot： | P17927 |
| Formulation： | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source： | Monoclonal, Mouse:IgG1, Kappa |
| Dilution： | IHC-p: 1:100-200 |
| Purification： | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Concentration： | 0.3mg:mL |
| Storage&Stability： | -20°C:1 year |
| Background： | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and:or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants. |
| Subcellular Location： | Membranous |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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