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Adrenocorticotropin(ACTH) (ABT-ACTH) mouse mAb Ready to use

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¥1900.00元/format:100ul

目录号:IML0065

库存:现货
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Catalog No. :IML0065
Reactivity:Human
Applications:IHC-p
Gene Name:POMC
Protein Name:Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin]
Human Gene Id:5443
Swiss-Prot:P01189
Formulation:Liquid in PBS containing, 0.5% BSA and 0.02% sodium azide.
Source:Monoclonal, Mouse:IgG1, Kappa
Dilution:Ready to use for IHC-p
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:nan
Storage&Stability:4°C: 1 years
Background:This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.
Subcellular Location:Cytoplasmic
BiowMW:nan

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