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PD-1 (ABT-PD1) mouse mAb

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¥1900.00元/format:100ul

目录号:IML0063

库存:现货
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Catalog No. :IML0063
Reactivity:Human; Mouse
Applications:IHC-p; IF(paraffin section)
Gene Name:PDCD1 PD1
Protein Name:Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)
Human Gene Id:5133
Swiss-Prot:Q15116
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Monoclonal, Mouse:IgG1, Kappa
Dilution:IHC-p: 1:100-1:200 IF: 1:50-1:200
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:0.185mg:mL
Storage&Stability:-20°C:1 year
Background:This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Subcellular Location:Membranous, Cytoplasmic
BiowMW:nan

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