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EnglishCatalog No. : | IML0063 |
Reactivity: | Human; Mouse |
Applications: | IHC-p; IF(paraffin section) |
Gene Name: | PDCD1 PD1 |
Protein Name: | Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) |
Human Gene Id: | 5133 |
Swiss-Prot: | Q15116 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Monoclonal, Mouse:IgG1, Kappa |
Dilution: | IHC-p: 1:100-1:200 IF: 1:50-1:200 |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 0.185mg:mL |
Storage&Stability: | -20°C:1 year |
Background: | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Subcellular Location: | Membranous, Cytoplasmic |
BiowMW: | nan |
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