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CD3 (ABT-CD3) mouse mAb Ready to use

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¥1900.00元/format:100ul

目录号:IML0013

库存:现货
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Catalog No. :IML0013
Reactivity:Human
Applications:IHC-p
Gene Name:CD3E T3E
Protein Name:T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3:Leu-4 epsilon chain) (CD antigen CD3e)
Human Gene Id:916
Swiss-Prot:P07766
Formulation:Liquid in PBS containing, 0.5% BSA and 0.02% sodium azide.
Source:Monoclonal, Mouse:IgG2b, Kappa
Dilution:IHC-p: 1:100-200 WB: 1:500-2000
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:nan
Storage&Stability:4°C: 1 years
Background:The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha:beta and gamma:delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Subcellular Location:Membranous
BiowMW:nan

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